the basic science of poisons Klaassen, Curtis D. editor. text bibliography nyu 2019 2019 Ninth edition. monographic eng

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xiii, 1620 pages : illustrations (some color) ; 29 cm "The gold-standard text on the science of poisons updated to capture the latest breakthroughs and developments Casarett & Doull's Toxicology: The Basic Sciences of Poisons is the most trusted all-in-one overview of the biomedical and environmental aspects of toxicology. Presented in full color, it delivers a skill-building review of the basic components of toxicology, including general principles, modes of action, and chemical-specific toxicity. Spanning the entire field, Casarett & Doull's is considered to be the ultimate authority in toxicology. The Ninth Edition has been extensively updated by each chapter author and is enhanced by the addition of all-new chapters on timely topics such as computational toxicology and auditory toxicology. The extensive use of tables, illustrations, and other visuals make the information easy to understand and remember"-- "This edition reflects the progress made in toxicology during the last few years. For example the importance of apoptosis, autophagy, cytokines, growth factors, oncogenes, cell cycling, receptors, gene regulation, protective mechanisms, repair mechanisms, transcription factors, signaling pathways, transgenic mice, knock-out mice, humanized mice, polymorphisms, microarray technology, second-generation sequencing, genomics, proteomics, epigenetics, exposome, microbiota, read across, adverse outcome pathways, high-content screening, computational toxicology, innovative test methods, organ-on-a-chip, etc. in understanding the mechanisms of toxicity and the regulation of chemicals"-- editor, Curtis D. Klaassen, PhD, DABT, ATS, FAASLD, University Distinguished Professor and Chair (Retired), Department of Pharmacology, Toxicology and Therapeutics, School of Medicine, University of Kansas, Kansas City, Kansas. Includes bibliographical references and index. Toxicology MEDICAL / Pharmacology RA1211 .C296 2019 615.9 KLA/C MED071000 New York : McGraw-Hill Education, [2019] Ninth edition. (DLC) 2018012790 9781259863745 1259863743 2018011899 DLC 180314 20210720115620.0 20405795 eng